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Many patients experience reduced appetite and fluid intake when starting GLP-1 therapy, whilst the medicine's gastrointestinal effects including nausea and occasional vomiting can further affect hydration status

It was first isolated and studied by Predrag Sikiric and colleagues at the University of Zagreb, whose group has authored the majority of published animal research on this compound over several decades

The measured position is that the pathway is important and GHK-Cu is pleiotropic, so overlap is likely but a clean, primary demonstration that GHK-Cu drives Wnt-dependent anagen in human follicles is not something the record firmly establishes