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In the context of early brain injury following subarachnoid hemorrhage (SAH), topiramate significantly reduced the elevated levels of TNF-, IL-1, and IL-6 induced by SAH, suggesting that topiramate may exert neuroprotection via its anti-inflammatory effects (Tian et al., 2015)

In addition, glucocorticoids in breast milk (cortisol and its inactive form cortisone) are closely linked to signaling pathways for processes such as energy balance, regulation of stress activity and immune function in the infant [17]

Glutathione stimulates vitamin D regulatory and glucose-metabolism genes, lowers oxidative stress and inflammation, and increases 25- hydroxy-vitamin D levels in blood: a novel approach to treat 25-hydroxyvitamin d deficiency

This subsequently results in increased glucagon granule assembly and secretion