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The vitamins and amino acids are naturally occurring and very well tolerated

The EGFP module in the sorting tag can also be replaced by other fluorescent proteins such as YFP, mCherry, mStrawberry, mOrange et al

Collectively, these observations highlight a convergent pathogenic mechanism in NDDs, in which mitochondrial quality control failure, through impaired mitophagy, defective protein import, and ROS-driven dysfunction, links mitochondrial damage, mtDNA-mediated inflammation, and protein aggregation [68,69,70,71,72,73]