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Younger animals typically exhibit higher levels of synaptic plasticity [21], more efficient neuronal signaling pathways [37], while aging, which is associated with declines in neurogenesis and reduced neural adaptive capacity, [22] which are related to impairments in cognitive function

Chen Y, Lu R, Zheng H, Xiao R, Feng J, Wang H et al

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Stable Isotope Labeling in Cell Culture To prepare medium including [ 13 C 3 ]-serine, RPMI 1640 Medium powder without glucose and amino acids (US Biological) and DMEM powder without glucose, glycine, and serine (US Biological) were reconstituted following manufacturers instructions