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Moreover, Tsg101, another component of the ESCRT complex, was shown to be indispensable, as deficiency of ALIX or Tsg101 led to the inability to repair damaged lysosomes and irreversible cell death 81

The follicle is made up of three main parts: The bulb is the bottom part of the follicle and contains the cells that produce new hair

Last reviewed: July 15, 2026 Last updated: July 15, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations