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Constant irritation can cause inflammation and permanent pigmentation

They study authors wrote: Neuropsychiatric symptoms are a well-described side effect of systemic corticosteroid therapy and can range from mild to severe. In this case including psychosis

Participants exhibited higher lymphocyte counts and increased levels of interleukin (IL)-2 and immunoglobulin G (IgG), while no significant changes were observed in IL-4 and IgA