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In conclusion, in vivo experiments on active compounds are mainly conducted on animals

Nair AR, Lee WK, Smeets K, Swennen Q, Sanchez A, Thevenod F, Cuypers A (2015) Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidney

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GS I- enzymes are generally found in low G + C gram-positive bacteria, thermophilic bacteria, and euryarchaeota, whereas GS I- enzymes are found in other bacteria species 16,17