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Nicotine and its metabolite, cotinine, can cross the blood-testis barrier, which subsequently causes harm of diverse degree to the germ cells

has dramatically declined in the last two decades, particularly among the countrys youngest residents

Virtually all serious cases can be attributed to improper use of nicotine replacement therapies like patches, gums, lozenges and inhalers

This indicates that there are multiple pathways from MSDP to psychopathology symptoms in childhood and adolescence. While offering a novel viewpoint on pediatric neurodevelopment, it suggests the importance of reducing MSDP to minimize the risk of associated mental health disorders in children