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The LOD and limit of quantification (LOQ) were calculated mathematically by the relationship between the standard error () of the calibration curve and its slope (S) using the multiplier according to ICH [50]ICH Q2 (R1), Validation of analytical procedures: text and methodology, in Proceedings of the International Conference on Harmonization, Geneva, Switzerland, 2005

Results: In the NAFLD group at the baseline, most participants were men (53%), 40% had type II diabetes, the mean age was 51 years and the distribution between fibrosis stages F0/F1/F2/F3/F4 was 3%/26%/36%/23%/11%

B12 shots give a direct boost of this key vitamin, bypassing the digestive system so more of it reaches the bloodstream

A., Sooch, G., Chen, X., White, F