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Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimers disease mouse model

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Famous producer Joseph Levine, president of Embassy Pictures (which made Zulu), told Caine the studio was not picking up his option because you look like a queer on-screen. (This, incidentally, was 1964, the same year Rock Hudson was ending his seven-year run as the top box-office attraction.) But Caines performance attracted the attention of producer Harry Saltzman, who cast him as spy Harry Palmer in the film of Len Deightons bestseller, The Ipcress File. The movie marks the beginning of Caine the icon