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Activation of the TLR2/MyD88/NF-B signaling pathway initiates a cascade of genes associated with inflammatory cytokines, such as IL-1, IL-8, and TNF-, thereby exacerbating hepatic injury [72]

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To identify L-serine-induced transcriptional changes along their development, we employed trajectory inference analysis to order CD4 T cells along a differentiation axis (Fig

The variable importance in projection (VIP) score plot for the top 15 most important metabolite features identified by partial least squares discriminant analysis (PLS-DA)