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Estimation of cancer risk associated with compensatory behaviors Our simulation suggests that the Cancer Risk Index (CRI) for formaldehyde [median (1 st quartile 3 rd quartile)] was 8.1 10 6 (3.6 10 6 1.7 10 5 ) when participants used a low nicotine concentration (6 mg/mL) without adjusting power (6F) and 4.1 10 6 (2.1 10 6 8.4 10 6 ) in the comparable power condition when using the higher nicotine concentration (18F)

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The risk of coronary heart disease is reduced by about half after the first year of cessation, falling to that of never-smokers after 15 years of abstinence (US Surgeon General, 1990)

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