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44-47 These effects of lower exposure manifest as reduced disturbances in biological processes associated with COPD (including oxidative stress, inflammation, and apoptosis), less severe adaptive changes in respiratory tissues, absence of alveolar destruction (emphysema), and reduced pulmonary dysfunction

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Many people who were smoking have been motivated to switch to these products, on the understanding that they can continue to consume nicotine but at much lower risk to their health

A massive problem for smokers is not only the nicotine addiction itself, but the quantity of nicotine that smoking takes into the body