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Lung cancer screening (LCS) is recommended for individuals at increased risk for lung cancer based on age and smoking history.1 LCS clinical trial data show that 50-55% of participants in these studies currently smoke cigarettes, and of those, up to 90% continue smoking after LCS.2 There is strong evidence that combining smoking cessation interventions with LCS is highly cost-effective, preventing deaths from lung cancer and other causes.3 Adding a cessation intervention with 15% abstinence effectiveness at the time of the first screen and assuming that 30% of eligible people undergo LCS is estimated to avert 2,422 additional lung cancer deaths in the 1960 US birth cohort.4 As the population ages, there will continue to be a demand for efficient and effective systems to offer smoking cessation on a large scale.5 Numerous cessation interventions and services have been shown to be effective globally.6 Until recently, it was unclear how to best design systems that could extend the reach of these treatments to maximize the integration of smoking cessation in the context of LCS

Beneficial effects of colestipol-niacin on coronary atherosclerosis

How cigarette smoke skews immune responses to promote infection, lung disease and cancer

Psychiatry 173 , 588599 (2016)