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Is Nicotine a Stimulant or Depressant? The Science & Definitions Is Nicotine a Stimulant or Depressant? Harmony Ridge Recovery Center WV Alcohol is a depressant. Alcohol might seem like a quick fix, but it actually interferes with your brain chemistry and can fuel anxiety. It affects serotonin and dopamine the brain chemicals Puffing away sadness Harvard Health
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