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According to the most recent WHO report, 2023 Antibacterial agents in clinical and preclinical development: an overview and analysis (data collected up to the end of 2023), there are nearly a hundred new chemical entities in the trials, out of which 26 are labeled as innovative depending on if they meet one or more of the four WHO criteria (new chemical class, new target, new mode of action or absence of cross-resistance) [59]

Environ Pollut 301:119001 Liang Y, Tse M, Young L et al (2007) Distribution patterns of polycyclic aromatic hydrocarbons (PAHs) in the sediments and fish at Mai Po Marshes Nature Reserve

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Unlike prior reviews, which often present descriptive overviews, this article emphasizes comparative evaluation of design principles, biological mechanisms, and translational hurdles, including biosafety, tumor heterogeneity, and large-scale manufacturability