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doi: 10.1136/gutjnl-2012-304216

10.1111/dth.13659 70

In addition to alterations in reverse cholesterol transport, our group also reported impaired HDL antioxidant activity in a wide array of pathologies such as metabolic syndrome, type 2 diabetes, obesity, iron deficiency, iron overload and rheumatoid arthritis (Martin et al., 2022

The result that Pdcd4 knockdown increased the distribution of p70s6k1 mRNA but not p70S6K2 mRNA in the polysomal fractions indicates Pdcd4 inhibiting p70S6K1 translation (Fig