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Although analyses and recommendations of renowned studies like The Multiple Risk Factor Intervention Trial (270), the North Karelia Project (374) and The China Study (375, 376) vary, the general conclusions of these and many other conclusive publications usually state that healthy dietary patterns are mainly plant-predominant

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Depending on the type of pathophysiologic process, water and sodium may be lost in physiologic proportion or lost disparately, with each type producing a somewhat different clinical picture, designated as normotonic (mostly isonatremic), hypertonic (mostly hypernatremic), or hypotonic (always hyponatremic) dehydration