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Neutrophil extracellular traps in tumor metabolism and microenvironment

4 The 2020 American College of Rheumatology guidelines 5 conditionally recommend screening for the human leukocyte antigen (HLA)-B*58:01 allele in certain populations before starting allopurinol, as carriers of this allele have a higher risk of TEN than noncarriers

Maintaining adequate glutathione levels is therefore essential for preserving cellular stability, particularly in tissues under heavy metabolic demand