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As such, while preclinical evidence supports the hypothesis that exercise can regulate oxidative stress and HPA axis function, the extent to which these findings can be generalized to human populations is still waiting to be investigated

Alcohol aggravates acute pancreatitis by impairing autophagic flux through activation of AMPK signaling pathway

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This dual regulation of SLC7A11 expression and activity creates a fine-tuning mechanism to modulate cell antioxidant capacity and lipid ROS during ferroptosis ( (with erastin, sulfasalazine, or sorafenib) or GPX4 (with RSL3, ML162, ML210, FIN56, or FINO2) can produce ROS in the absence of GSH depletion and trigger ferroptosis