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102 Studies have shown that mitochondrial dysfunction can lead to the occurrence of intestinal inflammation, 103,104 and excessive mitochondrial division inhibits the repair of the intestinal mucosa by disrupting butyrate metabolism in intestinal epithelial cells

In addition, discordant (oppositive) differential mRNA expression of genes associated to the IGF-1 signaling pathway has been observed in kidney samples from mice undergoing post-ischemic renal repair, compared to gene expression profiles reported in human renal cell carcinoma

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Increased prevalence of metabolic syndrome in uncontrolled hypertension across Europe: the global Cardiometabolic risk profile in patients with hypertension disease survey