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Six randomized, double-blind, placebo-controlled trials involving over 900 participants demonstrated that this growth hormone fragment peptide is well-tolerated with a safety profile indistinguishable from placebo

Some patients receiving intramuscular injections may experience localized injection site reactions such as pain, redness, or irritation, but serious injection site complications are uncommon

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and the conversion of 5-methyltetrahydrofolate to tetrahydrofolate, a process necessary for DNA synthesis and red blood cell production