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Therapeutic targeting of pyroptosis-related molecules, including NLRP3, caspase-1, GSDMD, and GSDME, represents a promising treatment approach for CD

The Predicted Aligned Error (PAE) plots were generated using Python 3.9 to visualise the predicted uncertainty in the relative positions of residues in the protein models

In laboratory research models, GSH exerts its antioxidant activity through direct scavenging of reactive oxygen species (ROS) and reactive nitrogen species (RNS), as well as through serving as an essential cofactor for glutathione peroxidase (GPx) enzymes, which catalyse the reduction of hydrogen peroxide and lipid hydroperoxides to non-toxic products