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( a ) Measurement of weight over the weeks of CORT/veh treatment and GDF11/saline injections (n Ctrl = 8 mice, n CORT = 16 mice, n GDF11 = 8 mice, n CORT-GDF11 = 16 mice)

Contraindication: Allergy, diagnosis of ETOH withdrawal unclear, and advanced cirrhosis with hepatic encephalopathy, Drug interaction with HIV treatment Caution patients who have received previous doses of benzodiazepine, phenobarbital will act synergistically, therefore need to start at low dose