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Compared to vehicle-treated cells, Rylaze treatment resulted in a 2-fold decrease in the percentage of cells in the S phase and a 3-fold decrease in the G2 phase, while the percentage of cells in the G1 phase increased 2-fold, indicating a stall in cell cycle progression ( Supplementary Figure S1D )

Local protein synthesis at synapses is required for the long-lasting physiological and pathophysiological sequelae of group I metabotropic glutamate receptor activation including some receptors proposed in mediating metaplasticity

Clinical studies have shown that MDA levels in serum and plasma samples of MASLD patients are significantly higher than in healthy individuals [133]

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