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Biological drugs such as monoclonal antibodies bind with high specificity to their target proteins

A possible infectious cause was first proposed as an explanation for this intriguing observation, but recent data have strengthened the genetic-immunologic theory (170, 174, 175)

In this study, 6 weeks of physical training or creatine supplementation (300 mg/kg, orally) decreased the duration of PTZ-induced seizures in rats, as measured by cortical and hippocampal electroencephalography and behavioral analysis