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Brain 147 , 16531666

Regarding acute toxicity, according to the 2023 National Poison Data System annual report, there were 7905 reported unintentional heavy metal exposures in the United States, resulting in 26 serious health outcomes and two deaths

This metabolic imbalance contributes to increased lipid peroxidation, as indicated by high malondialdehyde (MDA) levels ( These mitochondrial impairments not only compromise energy production but also act as pro-inflammatory stimuli, promoting chronic neuroinflammation through dysregulated mitochondrial signaling and innate immune response