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BMJ have an article "Guide to ethical approval" Search for "BMJ Guide to Ethical Approval" to find it

Thermo Fisher Scientific Inc

We [Beach House Center for Recovery] dont have a specific cut-off, but if someone comes in with a .29 BAC, in many cases well send them to the ER: we dont know if their respirations will decrease and they could die in their sleep from apnea. There are exceptions to this general rule