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However additional clinical and pharmacokinetic analyses are necessary to verify its long-term safety establish the ideal dosage and investigate any possible negative effects in human populations

doi: 10.1016/j.molcel.2015.06.011 11 AndrewsNCSchmidtPJ

It was suggested that ONOOH isomerises to NO 3 and H + either directly or indirectly via the radical intermediates NO 2 and OH (Goldstein and Merenyi, 2012)