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161 Beyond immune cell recruitment, hepatocyte-derived cholic acid triggers the release of Hedgehog ligands by HSCs, initiating Hedgehog signaling and promoting hepatocyte proliferation

These observations are consistent with the aforementioned redox analysis, which demonstrated that LDRT alone induces only limited oxidative stress due to compensatory intracellular antioxidant systems [24]

Abnormal mitochondria in salivary gland epithelial cells may act as DAMPs to trigger the formation of the local immune microenvironment ( pSS is one of the most prevalent systemic autoimmune diseases that is characterised by a triad of manifestations: dryness, pain and fatigue ( The salivary gland epithelium is composed of acinar cells, ductal cells, MECs and progenitor cells

37 (2), e111