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Polymicrobial enteric septicemia from coffee enemas

Histopathological analysis At the time of euthanasia, partial excised liver, tumor, and spleen samples were collected, and were fixed with total immersion in 10% neutral buffered formalin for 24h, then embedded in paraffin, and sectioned into 5-m slices and stained with Hematoxylin and Eosin (H&E)

The treatment was well tolerated, as we did not observe a difference in weight between RSL3 and vehicle groups (Fig

CHIP, a ubiquitin ligase that interacts directly with Hsp70/90, exhibits neuroprotective properties (174,175), and can inhibit toxicities linked to abnormal protein accumulation in Drosophila and mouse disease models (176)