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Nearly 30 systematic reviews and meta-analyses have been published regarding ALAs beneficial effects in managing diabetes and its complications (Table 4)

In India, Central Drug Standard Control Organization (CDSCO) has approved Glutathione for intravenous use in cases of alcoholic fatty liver, alcoholic liver fibrosis, alcoholic cirrhosis, and alcoholic hepatitis while Food and Drug Administration (FDA) The dose and duration of treatment by oral Glutathione varied in all the three studies.[12], [13], [14] Because of its antioxidant properties, it is also being used by some dermatologists for allergic disorders of the skin like eczema

Collectively, these studies highlight that pharmacological activation of Nrf2 can reduce ferroptosis and improve neurological deficits in preclinical models of ICH

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