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In this model, choline-deficient diet from 3 to 12 months of age disrupted liver and heart normal function, and altered neural networks associated with microtubule stability and postsynaptic membrane regulation in the hippocampus, elevated soluble and insoluble Amyloid- levels, increased Thioflavin S structures, and tau hyperphosphorylation at various pathological epitopes in the hippocampus and cortex (163)

Activation of the Nrf2-ARE pathway attenuates hyperglycemia-mediated injuries in mouse podocytes

Granulomatous inflammation is a defining feature of sarcoidosis and hypersensitivity pneumonitis, where antigen-driven immune responses lead to non-caseating granuloma formation and immune complex-mediated lung damage [7]

Table 1 Overview of human and animal studies on T cells with special regard to T reg cells