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Description

This microarray contains 304 antibodies against 147 phosphorylation sites of proteins involved in 16 signaling pathways

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33,34 Of the Smads, Smad2 and Smad3 have been shown to be the major downstream regulators involved in TGF-1-mediated tissue fibrosis

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While antioxidant and anti-inflammatory strategies show considerable promise, several important limitations must be acknowledged

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