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Methods: We crossed Cflar FF ;Alb-Cre mice with Fgf18 FF mice, resulting in the generation of hepatocyte-specific Cflar and Fgf18 double-deficient ( Cflar LKO ;Fgf18 LKO ) mice

Additionally, saturated fatty acids (SFAs), which are also common in UPFs such as processed meats, fried foods and baked goods, have been linked to chronic low-grade inflammation mediated by macrophage recruitment and release of inflammatory cytokines, notably tumor necrosis factor- (TNF-) and interleukin-6 (IL-6), which may contribute to neuroinflammation via crossing of the blood-brain-barrier (BBB) (32)

We therefore measured the Log D of ABA using absorbance measurements at 330 nm in an octanol/water partition assay

85 Changes in mitochondrial dynamics often induce more intense oxidative stress in return