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If plasma bilirubin concentrations are judged to be too high, phototherapy with blue-white light, which isomerizes bilirubin to more soluble pigments that might be excreted with bile, or exchange blood transfusion to remove the excess bilirubin, is necessary to avoid kernicterus

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Senescent cells can remain in the body and contribute to multiple diseases as well as features of aging, ranging from heart disease to frailty, dementias, osteoporosis, diabetes, and kidney, liver, and lung diseases