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Efficacy and safety of the combination of superoxide dismutase, alpha lipoic acid, vitamin B12, and carnitine for 12 months in patients with diabetic neuropathy

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In the presence of VEGF-A, untreated HUVECs almost completely migrated to the wound area after 24 h, but VGB4 treatment significantly decreased VEGF-A-induced migration by 79.7% and 85.7% at 0.55 M and 0.74 M, respectively, when compared to control and scr-treated cells ( P 0.001) (Fig

In addition, both L-glu uptake as well as EAAT2 immunoreactivity, as analyzed by Western blotting, were shown to be quantitatively reduced in postmortem tissue of ALS patients especially in the spinal cord, the tissue that is most affected by the disease (Rothstein et al., 1992