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Targeting orthotopic gliomas with renal-clearable luminescent gold nanoparticles

At the end of the experiment, mice were anesthetized with Avertin (300 mg/kg body weight) after 4 h of fasting

Biomimetic cell membrane coating combined with stroma-degrading enzymes (e.g., hyaluronidase) has increased accumulation to 15%22% ID/g in patient-derived xenografts, offering a promising solution ( Regarding clinical translation, several MSN-related nanoplatforms have entered human trials

found abundant expression of xCT on the surface of KSHV + PEL cells, which not only increases intracellular GSH levels to reduce oxidative damage caused by ROS but also activates the AKT pathway-dependent proliferation of B cells, ultimately promoting the progression of PEL