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Because it raises triglycerides and VLDL, produces inflammatory cytokines, increases blood pressure, and drives insulin resistance, visceral fat directly damages arteries and raises cardiovascular risk even in normal-weight individuals (Hall et al., 2015

In addition to the VN, T cells, B cells, dendritic cells (DCs), and macrophages in the follicular and marginal zones of the spleen are other major sources of ACh ( via exocytosis at specialized synaptic clefts ( Figure 1 The relative concentration of ACh in humans is found to be 8 clearance mediated via stimulation of microglial nicotinic acetylcholine receptors

(+ ve Control): LCA cell line (A549) was maintained in drug-free environment and were kept without treatment

Previous studies have demonstrated that electroconvulsive shock can activate microglia, upregulate proinflammatory cytokines, and enhance OS responses [38]