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We also asked if genetically increasing the glutaryl-CoA pool (the donor for glutarylation) altered glutaryl modifications and generated GCDH-deficient HeLa cells (Supplementary Fig

Additionally, UA has demonstrated neuroprotective effects against oxidative stress caused by hydrogen peroxide (H2O2), thereby safeguarding neuronal survival in the face of elevated levels of reactive oxygen species (ROS) (Figure 5)