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doi: 10.1038/s41586-022-05650-9

Curcumin inhibits the cancer-associated fibroblast-derived chemoresistance of gastric cancer through the suppression of the JAK/STAT3 signaling pathway

Often, these doses used often do not accurately reflect meaningful clinical exposures, as some commonly used 46 h doses in animal models may equate to a much longer exposure in humans (42, 166)