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More importantly, we found that the addition of GSH further accelerated the MB degradation process, indicating a tandem reaction between Cu-DMSA and GSH that promoted NP disassembly and enhanced the generation of ROS (Fig

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The hemophagocytic characteristics as defined above were associated with decreased survival, especially death in cytopenia [192], and the observations also support the hypothesis that increased ferritin levels at least for some AML patients reflect a specific AML-associated inflammatory phenotype

Thus, the importance of peroxynitrite as a mediator of oxidative stress in aging RBC remains questionable