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the highest FiO2 necessary to maintain a basal SaO296% before performing the 6MWT, is an independent risk factor associated with mortality in patients with IPF after one year of follow-up (consistent recommendation, very low quality evidence).72 Due to the lack of specific data in patients with IPF, it is recommended that long-term home oxygen therapy be administered when there is a finding of significant hypoxemia at rest or in the 6MWT (SaO288%) (consistent recommendation, very low quality evidence)

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Another group performed scratch wound assays and reported no impact of e-cigarette aerosol on endothelial cell migration, compared to concentration-dependent inhibition following exposure to cigarette smoke [16]