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4,5 Deleterious cellular effects triggered by proteostatic dysfunction are referred to as proteotoxicity, which is implicated in various human pathologies

All animal experiments in this study were performed in strict accordance with the institutionally approved protocol according to the USPHS Guide for the Care and Use of Laboratory Animals and with the approval of the Institutional Animal Care and Use Committee of the South China University of Technology

Usefulness of stable isotopes of its homeostasis Glutathione (GSH) plays an important role against free radicals, its blood concentration showing a strong correlation with in vivo oxidative stress

Curcumin was well-tolerated, had no adverse effects, and exerted an anti-rheumatic activity identical to that of phenylbutazone as shown by improvement in joint swelling, morning stiffness, and walking time