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doi: 10.1016/j.cell.2023.02.002

172 Creatine helps to maintain adequate ATP levels in tissues with high energy requirements and a specific creatine transporter is required for the uptake of creatine by cells

GLS1 is the main isoform expressed in cancer cells and has been shown to be upregulated in a wide variety of cancers, including breast, lung, cervix and brain [36]