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The utilization of the mitochondrial-targeted Frex sensor have allowed to measure cytoplasmic and mitochondrial free NADH levels (120 nM versus 30 M) confirming data obtained from measuring intrinsic autofluorescence (87)

The study discussed here was relatively small, involving only 17 patients, and more extensive clinical trials are needed to fully understand: Long-term safety profile Optimal dosing protocols Patient selection criteria Potential side effects Interactions with other treatments Additionally, patients should be aware that BPC-157 is not yet FDA-approved for human use, and treatment is typically offered on a research or compassionate use basis by qualified practitioners

doi: 10.1186/s13059-017-1271-6 17 CostelloMECicciaFWillnerDWarringtonNRobinsonPCGardinerBet al

Plus, vitamin-C, with its antioxidant properties, reduces the count of the free radicals, which cause oxidative stress and skin damage