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[DOI] [PMC free article] [PubMed] [Google Scholar] 292.Ribeiro R.V., Senior A.M., Simpson S.J., Tan J., Raubenheimer D., Le Couteur D., Macia L., Holmes A., Eberhard J., OSullivan J., et al

Metabolic Changes and Warfarin Just like changes of perfusion to the liver can alter how much drug (any drug, but obviously warfarin) is metabolized, there are certain disease states that can change the metabolic processes themselves (and, so, alter warfarins effects)