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10.1590/S0103-50532007000100015 J

McNeil BD, Pundir P, Meeker S, Han L, Undem BJ, Kulka M, et al

Intervention of high dose thiamine therapy in biochemical dysfunction in diabetes and the prevention of microvascular dysfunction, neuropathy, dyslipidemia complications Microvascular disease (nephropathy, retinopathy and neuropathy) a common debilitating manifestation of chronic diabetes mellitus, has no effective therapy