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Dasarathy, S

For a detailed understanding of the key regulatory factors in the ferroptosis-related pathway, including GPX4, System Xc-, NRF2, ACSL4, Coenzyme Q10, FSP1, and p53, refer to Fig

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Currently, several checkpoint inhibitors are approved by the US Food and Drug Administration, including cytotoxic T-lymphocyteassociated antigen 4 (CTLA-4) inhibitors and programmed cell death 1 (PD-1) or PD ligand 1 (PD-L1) inhibitors