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10.3109/10715762.2013.789136 Free Radic Res

Theoretical Long-Term Risks TB500 enhances angiogenesis and cellular proliferation, which has raised concerns primarily in preclinical models about: Accelerating growth of dormant tumors Disrupting immune surveillance Overstimulating wound healing in healthy tissues There is no conclusive evidence that TB500 causes cancer, but its role in cell migration warrants caution, especially at high doses or long-term use without breaks

M., Boltz, T., Francia, M., Bot, M., Ramesh, N

In clinical trials of ketorolac or another NSAID, heart failure, palpitations, pallor, sinus tachycardia, and syncope were reported in less than 1% of patients